A Highly Sensitive Adsorptive Stripping Voltammetric Method for Simultaneous Determination of Lead and Vanadium in Foodstuffs

This work describes a procedure for the simultaneous determination of vanadium and lead in some food and water samples using adsorptive stripping voltammetric method. The method is based on the adsorptive accumulation of cupferron complexes of these elements onto hanging mercury drop electrode, followed by reduction of adsorbed species by voltammetric scan using differential pulse modulation. Optimal analytical conditions were found to be cupferron concentration of 8.00 × 10⁻⁵ M, pH of 4.8 (phosphate buffer), an accumulation potential at −100 mV, and a scan rate of 80 mV s⁻¹. With an accumulation time of 50 s, the peak currents proportional to the concentration of lead and vanadium over the 0.05–80.00 and 0.10–105.00 ng mL⁻¹ ranges with detection limit of 0.02 and 0.01 ng mL⁻¹, respectively. The procedure was applied to simultaneous determination of vanadium and lead in some food and water samples with satisfactory results.     

Investigation on Physicomechanical,Thermal, and Morphological of Dipodal Silane-Modified Walnut Shell Powder-Filled Polyurethane Green Composites and Their Application for Removal of Heavy Metal Ions from Water

Dipodal silane-modified walnut shell powder polyurethane green composites have been prepared with different weight fractions of walnut shell powder viz., 0, 3, 6, and 10?wt% with surface-modified dipodal silane. The properties of dipodal silane-modified walnut shell powder-filled polyurethane green composites was investigated by tensile testing, Fourier transform infrared spectroscopy, thermogravimetric analysis, and scanning electron microscopy. The polyurethane/dipodal silane-modified walnut shell powder has been fabricated based on 3-aminopropyltriethoxysilane and γ-glycidoxypropyl trimethoxysilane. The green composites were analyzed by ultraviolet–visible in two different water solutions with Ni²⁺ and Pd²⁺ ions concentrations.     

Effect of Build Height on Temperature Evolution and Thermally Induced Residual Stresses in Plasma Arc Additively Manufactured Stainless Steel

Metallurgical and Materials Transactions A - Plasma arc additive manufacturing (PAM) is receiving an increasing attention because of its efficiency of dimensional size and cost, as compared to...     

HSA loaded with CoFe2 O4 /MNPs as a high‐efficiency carrier for epirubicin anticancer drug delivery

Drug delivery is one of the most important challenges in the domain of health. Non‐toxic and biocompatible carriers are provided by human serum albumin nano‐capsule (HSA/NC) for drug delivery applications. In this study, HSA, with high loadings of drug‐modified cobalt ferrite (CoFe₂ O₄) magnetic nanoparticle (CoFe₂ O₄ /MNPs) was fabricated for epirubicin anticancer drug delivery. In the initial step, CoFe₂ O₄ /MNPs was synthesised via co‐precipitation technique and characterised by X‐ray powder diffraction, vibrating sample magnetometry, energy dispersive X‐ray analysis, scanning electron microscopy and map analysis. Furthermore, CoFe₂ O₄ /MNPs and epirubicin were loaded into HSA/NC and utilised as a novel system against breast cancer cell line (MCF‐7). IC₅₀ for free epirubicin, unloaded CoFe₂ O₄ /MNPs/HSA/NC, CoFe₂ O₄ /MNPs and epirubicin‐loaded CoFe₂ O₄ /MNPs/HSA/NC were 7.7, 2400, 840 and 430 μg/ml, respectively. The results obtained revealed high cytotoxicity effect of epirubicin‐loaded CoFe₂ O₄ /MNPs on breast cancer cell line.Inspec keywords: drug delivery systems, biomedical materials, nanoparticles, cobalt compounds, ferrites, nanomedicine, proteins, molecular biophysics, drugs, magnetic particles, nanomagnetics, nanofabrication, precipitation (physical chemistry), X‐ray diffraction, X‐ray chemical analysis, scanning electron microscopy, cancer, cellular biophysics, toxicology, magnetic hysteresisOther keywords: HSA, high‐efficiency carrier, epirubicin anticancer drug delivery, human serum albumin nanocapsule, drug‐modified cobalt ferrite magnetic nanoparticle, coprecipitation technique, X‐ray powder diffraction, vibrating sample magnetometry, energy dispersive X‐ray analysis, scanning electron microscopy, map analysis, breast cancer cell line, cytotoxicity effect, CoFe₂ O₄      

Preparation and Characterization of Carvacrol Loaded Polyhydroxybutyrate Nanoparticles by Nanoprecipitation and Dialysis Methods

In this investigation, preparation of carvacrol loaded polyhydroxybutyrate (PHB) nanoparticles was performed by nanoprecipitation and dialysis methods. PHB particles were obtained by nanoprecipitation method without and with low concentration of Tween 80 or pluronic as surfactant. Nano‐ and micro‐sized particles were formed with trimodal distribution and large aggregates. Size and distribution of nanoparticles were decreased when concentration of Tween 80 was increased to 1% (v/v) in water as polar phase. PHB nanoparticles had narrow size (157 nm) with monomodal distribution. Nanoparticles, which were prepared by dialysis method had 140 nm in diameter with monomodal distribution. Carvacrol was used as a lipophilic drug and entrapped in optimized nanoparticles formulation by nanoprecipitation and dialysis methods. Entrapment efficacy was 21% and 11%, respectively. Morphology of PHB nanoparticles was spherical. The results of kinetic release study showed that carvacrol was released for at least 3 days. Release kinetic parameters showed a simple Fickian diffusion behavior for both formulations. Carvacrol loaded PHB nanoparticles had good dispersion into the agar medium and antimicrobial activity against Escherichia coli. This study describes the 1st work on loading of carvacrol into the PHB nanoparticles by nanoprecipitation and dialysis methods.